Elavil belongs to a category of drug known as Tricyclic antidepressants. It is used to treat depression. In depression patient behave abnormal, frequent mood change, abnormal eating or sleeping habits, negative thought, violent. This medicine works on the central nervous system (CNS) to uplift the mood of people with depression. It may start to show its effect within 3 to 4 days, but it may take up to 30 days to see the complete effects.
In Elavil, Amitriptyline is the core drug. It belongs to the category of TCA. It inhibits the reuptake of norepinephrine and serotonin. It works by keeping the level of serotonin and norepinephrine normal. Low level of neurotransmitter is the major cause of depression.
The use of this drug in contraindicated in certain condition-
- In case of any sensitivity to Amitriptyline or any of its constituents
- Not to be used in adolescent or child under the age of 12 years
- In case of taking Monoamine Oxidase Inhibitors (MAOIs), such as phenelzine,in the last 14 days
- In case of recent heart attack or stroke or kidney, liver disorder
- Avoid in case you are pregnancy or breast feeding ,it may harm the baby
Some of the drugs that interact with this drug and alter its desirable effects
- Avoid intake of Monoamine Oxidase Inhibitors MAOIs such as phenelzine, linezolid.
- Avoid intake of selective serotonin reuptake inhibitors such as citalopram
- Avoid intake of medicines used to treat fungal infections ketoconazole and itraconazole,
- Avoid intake of anti-epileptic drug such as Carbamazepine
- It should be stored at room temperature in a range of 15-30 degree centigrade.
- It should be kept away from the sight of children and pets
Elavil comes in the dose of 10mg, 25mg, 50mg, 75mg, and 25mg sustained release, 50mg sustained release.
It is recommended to take initial starting dose of Elavil for depression in adult’s patient is 25 mg 3 times a day with glass of water. It can be taken with or without food. Don't take it more than the recommended dose as it may cause Overdose symptoms include nausea, dizziness, vomiting, uneven heartbeat, drowsiness or sleepiness, tremor (shaking), agitation, and change in size of pupil.
Some serious side effects include swelling in hands, ankles, feet, agitation, aggression, blurred vision, anxiety, painful erection, depression, problems in speaking, feeling sick, throat, taste illness, feeling thirsty, burping, hiccups, hemorrhoids and sleepiness.
- Avoid intake of alcohol because this drug leads to drowsiness.
- Avoid driving or any machinery work, because this drug may impair your thinking.
- Don’t share your drug with anyone else.
- Used with caution in patient above 50 years of age.